McGuffin is the inspector hired by Charles Wagner to investigate the strange deaths in Dante Manor. He is thrown off the estate together with deputy Terrence when the investigations run into a dead end.

McGuffin is the one who retrieves Lucius from the burning Dante Manor after (depending on the ending you choose) either shooting Charles Wagner (who was about to kill Lucius) or either watching Lucius emerge from the burning building.

In Lucius II: The Prophecy, McGuffin becomes Lucius' protector, after Lucifer convinces him that everything that is going to happen (possibly the armagedon) was God's plan all along.